Tiny microbes and molecular machines have an outsized impact on human health, and they play key roles in the vast global cycles that shape climate and make carbon and nitrogen available to all living things.
This illustration shows arrestin (yellow), an important type of signaling protein, while docked with rhodopsin (orange), a G protein-coupled receptor.
(Greg Stewart/SLAC National Accelerator Laboratory)
The lab is responding to the coronavirus crisis by imaging disease-related biomolecules, developing standards for reliable coronavirus testing and enabling other essential research.
This new technology could enable future insights into chemical and biological processes that occur in solution, such as vision, catalysis and photosynthesis.
An LCLS imaging technique reveals how a mosquito-borne bacterium deploys a toxin to kill mosquito larvae. Scientists hope to harness it to fight disease.
The 1950s and ‘60s poisoning event was long attributed to methylmercury, but studies at SLAC suggest a different compound was to blame. The findings...
A better understanding of this phenomenon, which is crucial to many processes that occur in biological systems and materials, could enable researchers to develop...
Cryogenic electron microscopy can in principle make out individual atoms in a molecule, but distinguishing the crisp from the blurry parts of an image...
A new understanding of the nucleation process could shed light on how the shells help microbes interact with their environments, and help people design...
A better understanding of ‘checkpoint proteins,’ which protect cancer cells against immune system strikes, could lead to the development of more effective drugs.
The lab is responding to the coronavirus crisis by imaging disease-related biomolecules, developing standards for reliable coronavirus testing and enabling other essential research.
This new technology could enable future insights into chemical and biological processes that occur in solution, such as vision, catalysis and photosynthesis.
An LCLS imaging technique reveals how a mosquito-borne bacterium deploys a toxin to kill mosquito larvae. Scientists hope to harness it to fight disease.
The 1950s and ‘60s poisoning event was long attributed to methylmercury, but studies at SLAC suggest a different compound was to blame. The findings could reshape toxicologists’ understanding of disease related to mercury poisoning.
A better understanding of this phenomenon, which is crucial to many processes that occur in biological systems and materials, could enable researchers to develop light-sensitive proteins for areas such as biological imaging and optogenetics.
Cryogenic electron microscopy can in principle make out individual atoms in a molecule, but distinguishing the crisp from the blurry parts of an image can be a challenge. A new mathematical method may help.
A new understanding of the nucleation process could shed light on how the shells help microbes interact with their environments, and help people design self-assembling nanostructures for various tasks.
What they learned could lead to a better understanding of how antibiotics are broken down in the body, potentially leading to the development of more effective drugs.
A better understanding of ‘checkpoint proteins,’ which protect cancer cells against immune system strikes, could lead to the development of more effective drugs.